Inclusion Body Fibromatosis : Clinical Features

Comments:
Clinical Features: Inclusion body fibromatosis presents as a small (usually < 1 cm), rapidly growing, nontender, dermal or subcutaneous nodule covered with smooth glistening skin. They are usually found on the dorsal or lateral aspect of fingers or toes near distal or middle phalangeal joints. They may impair joint movements or cause joint deformity (as seen in right half).

Multiple lesions may arise synchronously or separately on more than one digit. Sometimes, both fingers and toes may be involved. Other rare sites of involvement include upper arm, oral cavity and breast. Most cases occur by the age of 3 years (median age at diagnosis 12 months). About one-third of lesions are congenital. Rare cases occur in older children, adolescents or adults. There is no sex predilection.

Image courtesy of Dr. Ibrahim Zardawi; used with permission.