GIST in NF1
Gastrointestinal stromal tumors (GIST) are seen in about 7% of neurofibromatosis 1 (NF1) patients. They show somatic inactivation of wild-type NF1 allelle but lack the PDGFRA and c-kit mutations seen in typical GIST. Image courtesy of: Cody Carter, MD, Dept. of Pathology, Univ. of Michigan, Ann Arbor, Michigan.
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