Necrotic Seminoma : PLAP Immunostain
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![Testis_Seminoma_Necrotic_PLAP2.jpg](/slides-13/slides/Testis_Seminoma_Necrotic_PLAP2.jpg)
Comments:
Seminomas may retain immunoreactivity for some markers, such as PLAP, even after necrosis. The left half shows a completely necrotic tumor nodule. The ghost outlines of necrotic cells are visible. The right panel shows retained immunoreactivity for PLAP in tumor cells. Higher magnification of the previous image.