Primary Breast Angiosarcoma
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![Angiosarcoma92_Breast.jpg](/slides-13/slides/Angiosarcoma92_Breast.jpg)
Comments:
This focus shows low-grade angiosarcoma infiltrating breast adipose tissue. The lesion is subtle and may be missed. It consists of delicate, irregularly-shaped, variably dilated, anastomosing vascular channels lined by flattened endothelium lacking atypia. Such areas may be misdiagnosed as hemangioma or angiolipoma in core biopsies. Low-grade angiosarcomas of the breast are difficult to diagnose on limited material of needle biopsies. One should consider excising all low-grade vascular lesions of breast (except the most obvious perilobular hemangiomas) to avoid underdiagnosis of angiosarcomas.