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Telangiectatic Osteosarcoma

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The histologic features of telangiectatic osteosarcoma resemble an aneurysmal bone cyst. Blood filled cystic spaces are separated by delicate septa. However, unlike in an aneurysmal bone cyst, the cells lining the septa are cytologically malignant. Osteoid production is minimal or even absent. However, when metastases develop, they usually produce matrix.

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