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Seminoma : Syncytiotrophoblastic Cells

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Testes_Seminoma42_Syncytiotrophoblast.jpg

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A huge syncytiotrophoblastic giant cell with hundreds of nuclei is seen in this image. It is surrounded by typical seminoma cells and lymphoid infiltrate. Syncytiotrophoblastic giant cells are positive for beta-hCG immunostain. There is no evidence that classic seminomas containing syncytiotrophoblastic elements behave any more aggressively than tumors lacking them.

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