Fibrous Histiocytoma
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![SoftTissue_Fibrohistiocytic_Dermatofibroma3.jpg](/slides-13/slides/SoftTissue_Fibrohistiocytic_Dermatofibroma3.jpg)
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Fibrous histiocytomas do not have sharply defined borders. They usually show entrapment of surrounding dermal collagen. Fibrous histiocytomas contain Factor XIII-a +ve cells and are negative for CD34. DFSP's lack significant number of Factor XIII-a +ve cells and express CD34 in the majority of tumor cells.