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Mantle Cell Lymphoma

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This patient with mantle cell lymphoma presented with massive splenomegaly. Splenectomy showed diffuse white-gray nodules measuring 0.1 to 0.3 cm. Low-power view shows marked expansion of the mantle zone and tiny residual germinal centers. The lymphoid cells were CD20 positive and showed t(11;14)(q13;q32) translocation.

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