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Rhabdoid Tumor : Cytokeratin

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Kidney_Pediatric_RhabdoidTumor14_CK.jpg

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Immunohistochemistry: Rhabdoid tumor of kidney (RTK) shows positivity for vimentin, cytokeratin and EMA (especially in rhabdoid paranuclear inclusions). This example shows strong, focal positivity for cytokeratin. SMA, desmin, and S-100 protein are negative. Myogenin and neuroendocrine markers are sometimes expressed.

Image courtesy of Dr. Jean-Christophe Fournet, Paris, France; humpath.com

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