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Chondrosarcoma, Grade II

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Bone_Chondrosarcoma33_GrII.jpg

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The grading of chondrosarcomas is done on the basis of cellularity and atypia. Mitotic figures are uncommon and are not used in the grading. The tumor shown in the photomicrograph is a Grade II chondrosarcoma given the cellularity and pronounced atypia. Binucleated cells and prominent nucleoli are present. Between 30% and 40% of all chondrosarcomas are Grade II. Higher magnification of the previous image.

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