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Glioblastoma : Pseudopalisading

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Brain_Astrocytoma_GBM8_Pseudopalisading(1).jpg

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The presence of necrosis is one of the histologic hallmarks of glioblastoma. Necrotic areas are usually seen in serpentine pattern (shown here) or geographic pattern in hypercellular foci. Tumor cells often aggregate around the periphery of necrotic areas creating pseudopalisading.

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