Basal Cell Adenoma : Molecular Genetics


Comments:
Basal cell adenoma is characterized by CTNNB1(beta-catenin) gene mutation and loss of heterozygosity at 16q12-13 This low power image of a basal cell adenoma shows a trabecular pattern of growth characterized by ribbon-like areas. The intervening areas between the basaloid cell islands show eosinophilic basement membrane-like material.