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Pindborg Tumor : Introduction

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Calcifying epithelial odontogenic tumor (CEOT) (aka Pindborg tumor) makes up less than 1% of all odontogenic tumors. Despite clearly being odontogenic, its cell of origin is uncertain. Possible candidates include cells of the stratum intermedium of the enamel organ or the remnants of dental lamina. Some cases show mutations in PTCH1 gene which is associated with nevoid basal cell carcinoma syndrome, although CEOT is not a component of this syndrome.

This clinical image shows a huge swelling on the right side of the face of a 38-year-old female patient diagnosed with calcifying epithelial odontogenic tumor. Front view shows the swelling extending from the right ramus (arrow black outline) crossing the midline up to the left parasymphysis region (solid black arrow) of the mandible.

Image source: Misra et al. Giant Pindborg Tumor (Calcifying Epithelial Odontogenic Tumor) : An Unusual Case Report with Radiologic-Pathologic Correlation. J Clin Imaging Sci 2013, 3:11. Used under the terms of Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License.

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