Striving to be the most comprehensive online resource for high-quality pathology images

 

Pulmonary MALT Lymphoma : Introduction

prev  
slide 81 of 100
next
No Image
HemePath_MALToma_Lung6.jpg

Close

Comments:
Introduction: Pulmonary extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a low-grade B-cell lymphoma that recapitulates architecture of MALT. It has also been referred to as bronchus-associated lymphoid tissue (BALT) lymphoma. The term pseudolymphoma is no longer used.

Primary pulmonary lymphomas constitute 0.3% of all primary lung neoplasms, less than 1% of all lymphomas and about 3.6% of all extranodal lymphomas. MALT lymphomas make up 70-90% of all cases of primary pulmonary lymphomas. They are seen in middle-aged or elderly patients (median age 68 years) and are rare below the age of 30 years. About 30% of patients have an underlying autoimmune disorder such as Sjogren syndrome. Any location with the lung can be involved, including visceral pleura. Some lesions are localized entirely within the bronchus (endobronchial).

This low magnification view of a pulmonary MALT lymphoma shows nodular architecture due to colonization of residual benign germinal centers by neoplastic lymphocytes. The nearby alveolar spaces are filled with inflammatory cells and fluid (consolidation).

prev
slide 81 of 100
next