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Urothelial CA - Lymphoepithelioma-like

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At higher magnification, the tumor shows syncytial and trabecular growth patterns. The inflammatory component consists of lymphocytes, eosinophils, and a few plasma cells. Pure forms of lymphoepithelioma-like variant of urothelial carcinoma were initially thought to respond better to chemotherapy and considered to have a better prognosis. More recent studies do not fully support this view. Most cases present at advanced stages. An association with EBV has not been found to date.

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