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Cardiac Fibroma : Microscopic Features

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Microscopic Features: Cardiac fibromas are composed of bland fibroblastic cells in a dense collagenous stroma. There is no cytologic atypia or increased mitotic activity. At the periphery of the tumor, entrapped cardiac myocytes are frequently seen. Sometimes they are found deep within the tumor. The central area of the tumor is frequently hyalinized and shows calcification and myxoid degeneration. In this image, the lighter pink areas on the right are tumor and the darker pink areas on the left are myocardium.

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