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Lipoblastoma

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Soft Tissue_Lipomatous_Lipoblastoma2.jpg

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High power view from the previous image showing mature adipocytes separated by small amount of myxoid matrix and arranged in lobules. Cytogenetically, lipoblastomas show rearrangements of 8q11-13 (involving PLAG1 gene) or polysomy of chromosome 8. Prognosis is excellent. Cases of diffuse lipoblastomatosis may recur if incompletely excised.

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