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Spindle Cell Lipoma : Clinical Features

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Clinical Features: Spindle cell/pleomorphic lipomas are most commonly seen in the 45-60 yr. age group with a strong male predilection They are rare in children or adolescents.

The most common locations (80% of cases) are posterior neck, shoulder, and upper back. About 20% of cases involve limbs, face, trunk, and oral cavity. Most tumors are present in the subcutaneous tissues. Some are centered in the dermis. They are more likely to occur in women. Rare cases are entirely intramuscular.

They present as a slow-growing, solitary, firm, painless subcutaneous nodule. Rare cases have multiple lesions which may be synchronous or metachronous. The initial tumors in these patients occur at the typical locations, with more lesions arising on upper neck, shoulders, arms, chest, and axillae.

This low magnification view of a spindle cell lipoma shows an admixture of spindle cell areas and mature adipose tissue.

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