Mammary Paget Disease : Additional Image
Paget disease (PD) of breast usually presents as red or pink, eczematous, scaling, pruritic lesion of the nipple-areola complex. As the disease progresses, there is bleeding, ulceration, and bloody or serosanguinous discharge from the nipple. The nipple can become deformed or inverted and may be completely destroyed in advanced cases (as shown in this mastectomy specimen). In about 15% of cases, there are no nipple-related symptoms. Tumor nodules can appear in later stages. There are pigmented forms of PD (especially in males) which are frequently mistaken clinically for melanoma or eczema. Image courtesy of: Dr. Ibrahim Zardawi; used with permission.