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Silicone Mastitis

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Leakage of silicone gel into the breast parenchyma from a ruptured implant incites an inflammatory response that may be diffuse (silicone mastitis) or produce nodular lesions (silicone granulomas).

The cut surface of a breast specimen with silicone mastitis shows firm fibrotic tissue containing numerous cystic spaces filled with pale viscous material (silicone). The specimen may have a gritty feeling when cut if there is extensive calcification.

Image courtesy of: Rola Ali, MD, FRCPC, Associate Professor of Pathology, Kuwait University, Kuwait; used with permission.

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