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Cirrhosis in Hepatitis B

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Liver_Cirrhosis_HepB1_IntracellulalrCholestasis.jpg

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Chronic hepatitis B infection often results in cirrhosis with nodules of damaged and regenerating hepatocytes separated by fibrous bands containing chronic inflammatory cell infiltrates. The damaged hepatocytes are enlarged with ground-glass cytoplasm (containing abundant hepatitis B surface antigen particles) and bile pigment accumulation.

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