Myxoid Liposarcoma : Clinical Features

Comments:
Clinical Features: Myxoid liposarcoma (LPS) occurs in a slightly younger age group than atypical lipomatous tumor/well-differentiated liposarcomas and dedifferentiated liposarcomas. The peak incidence in the 5th decade. There is no sex predilection. LPS are extremely rare in the pediatric age group, but when they do occur, they are usually myxoid type.

The patients present with a large, painless, slow-growing mass in the deep soft tissues of the lower extremities (75% of cases), especially the medial thigh and popliteal fossa. It is quite uncommon in the retroperitoneum and subcutis. Retroperitoneal myxoid LPS usually represents metastasis.

The image shows a large myxoid liposarcoma resected from the thigh region. This was a recurrence. Note the scar from the previous resection. Image courtesy of: Dr. Ibrahim Zardawi; used with permission.