Striving to be the most comprehensive online resource for high-quality pathology images

 

Chronic Calculous Cholecystitis

prev  
slide 38 of 74
next
No Image
ChronicCholecystitis14_RA_Sinuses_resized.jpg

Close

Comments:
Rokitansky-Aschoff (RA) Sinuses: They are herniations of gallbladder mucosa into or even through the smooth muscle layer. The glands are usually oriented perpendicular to the lumen. They are gallbladder counterparts of intestinal diverticula. They usually form in response to increased intraluminal pressure due to bile outflow obstruction caused by gallstones. The presence of RA sinuses does not equate to chronic cholecystitis. They are also found in patients with biliary dyskinesia.

This image shows mucosal glands (RA sinuses) deep within the muscularis with no apparent connection to the surface. Given their location and the presence of fibrosis around glands in some cases, they may be mistaken for invasive adenocarcinoma.

prev
slide 38 of 74
next