11,716 Images : Last Update : Aug 13, 2022

Melanoma : Vertical Growth Phase

prev
slide 12 of 62
next
No Image
Skin_Melanoma_VerticalGrowthPhase2.jpg

Close

Comments:
Vertical growth phase of melanomas consists of cohesive nests, clusters, and nodules of tumor cells invading the dermis. The nests are larger and morphologically different than those in the intraepidermal component with greater pleomorphism, apoptosis and frequent mitoses. Features of regression are usually absent from the tumor base. Vertical growth phase is associated with greater potential for lymphovascular invasion, metastatic spread and adverse prognosis.

prev
slide 12 of 62
next