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Medullary Carcinoma

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Comments:
Syncytial clusters of tumors cells are surrounded a prominent lymphoplasmacytic infiltrate which is composed of peripheral T-cells (with numerous activated cytotoxic lymphocytes) and IgA-producing plasma cells. It is believed to be host reaction to the tumor and is thought to play a role in greater response to chemotherapy and improved survival rates seen with this tumor as compared to other breast cancers.

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