Image Description
Morphology: The neoplastic lymphocytes in primary cutaneous follicle center lymphoma show diffuse growth pattern (most common; 64% of cases) or follicular and diffuse or predominantly follicular pattern (least common; shown here).
The neoplastic follicles have the following features:
The neoplastic follicles have the following features:
- closely spaced together
- irregular, ill-defined borders
- poorly-formed or absent mantle zones
- monotonous appearance; no differentiation into polarized light and dark zones
- few or no tingible body macrophages
- lower proliferation rate than reactive germinal centers