Image 15 of 28



Image Description

The patient was a 65 y/o female with a history of uterine malignancy treated by radiation in the 1950's. She presented with gross hematuria and was found on cystoscopy to have a reddish tumor in the bladder wall. The image shows variably-sized vascular channels lined by atypical endothelial cells under an uninvolved intact urothelium. Immunostaining with CD31 and CD34 was positive in the atypical cells confirming the diagnosis of angiosarcoma.

Image 15 of 28