Striving to be the most comprehensive online resource for high-quality pathology images

 

DLBCL : Central Nervous System

prev  
slide 88 of 89
next
No Image
HemePath_DLBCL_CNS11_Apoptosis.jpg

Close

Comments:
Primary central nervous system lymphoma (PCNSL) is characterized by perivascular growth of large atypical lymphoid cells. With continued proliferation, the distribution becomes more diffuse and sheet-like.

If the patient is given steroid therapy before biopsy, the tumor may shrink considerably and show prominent apoptosis and necrosis (as demonstrated here). The biopsy material may consist predominantly of reactive T-cell mimicking a chronic inflammatory process. Therefore, if PCNSL is suspected clinically, steroid therapy should not be prescribed before establishing the diagnosis.

Additional images of primary CNS lymphomas are here

prev
slide 88 of 89
next