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Spindle Cell Carcinoma : Fibrosarcoma-like

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Breast_CA_Metaplastic10.jpg

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The spindle cell elements in metaplastic breast carcinomas infiltrate in between non-neoplastic ducts and lobules, especially at the tumor periphery. In contrast, sarcomas of extramammary origin that metastasize to the breast destroy the native breast architecture instead of entrapping epithelial elements.

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