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Clear Cell Carcinoma

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Ovary_CCC37.jpg

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Clear cell carcinomas (CCC) of the ovary usually show moderate to severe cytologic atypia consisting of eccentric hyperchromatic nuclei and prominent nucleoli. All CCC are considered high-grade by default. In this image, highly pleomorphic tumor cells are seen lining glandular spaces as well as infiltrating singly through the stroma.

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