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Anaplastic Meningioma

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Brain_Meningioma_Atypical1.jpg

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Anaplastic meningioma, also known as malignant meningioma, is a Grade III tumor according to the WHO that presents with either of two criteria: (1) greater than or equal to 20 mitoses per 10 HPF and/or (2) frank anaplasia (sarcoma, carcinoma or melanoma-like histology). In this picture, the majority of the cells are pleomorphic giving this tumor a sarcomatoid appearance.

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