Striving to be the most comprehensive online resource for high-quality pathology images

 

Schwannoma : Ancient Change

prev  
slide 38 of 62
next
No Image
Schwannoma_DegenerativeChange_Cystic3.jpg

Close

Comments:
Deep-seated schwannomas (mediastinum or retroperitoneum) of long standing may show several degenerative changes. They include degenerative-type cytologic atypia (irregularly enlarged multilobed hyperchromatic nuclei, intranuclear vacuoles), cystic change, calcification, hemorrhage, and dense hyalinization. The hyalinized stroma frequently contains hemosiderin-laden macrophages and inflammatory cells. Despite the cytologic atypia, mitotic activity is not increased. These changes have no prognostic significance.

This image shows areas of cystic change surrounded by cellular Antoni A areas.

prev
slide 38 of 62
next