Ganglioneuroma : Leydig Cells

Comments:
Rare cases of adrenal ganglioneuromas have been reported to contain Leydig cells as seen here. Such tumors may present with virilizing symptoms in female patients.

References: 1) Godlewski G et al. Virilizing adrenal ganglioneuroma containing Leydig cells. Acta Chir Belg 1993 Jul-Aug; 93(4):181-4.
2) Aguirre P, Scully RE. Testosterone-secreting adrenal ganglioneuroma containing Leydig cells. Am J Surg Pathol 1983 Oct; 7(7):699-705.