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Angiolipoma : Clinical Features

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Clinical Features: Angiolipomas occur in young adults (late teens or early 20's) with a male predominance. They are uncommon in children and adults > 50 yrs. About 5% cases are familial with an autosomal dominant pattern of inheritance.

They present as multiple, painful or tender subcutaneous nodules on the forearm (two-thirds of cases), arm or the trunk. If the vascular component is predominant, it may impart a bluish-purple discoloration to the overlying skin (clinical features continued in the next image).

The image shows a branching vascular network of capillary-caliber vessels separating mature adipocytes. The darker eosinophilic areas near the center and lower left are microthrombi within the vessels - an important diagnostic clue.

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