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Leydig Cell Tumor : Calretinin

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Testes_LeydigCellTumor1_Calretinin.jpg

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Calretinin is a calcium binding protein that was initially discovered in the neurons. It plays a role in calcium signaling. It is quite useful in distinguishing malignant mesothelioma (calretinin-pos) from adenocarcinoma.

The image shows cytoplasmic and nuclear staining for calretinin in a Leydig cell tumor of the testis.

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slide 19 of 104
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