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HMWCK in Adenosis

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Prostate_Immuno11B_HMWCK_AAH.jpg

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With high molecular weight cytokeratin immunostain, fragmented basal cell layer is seen in at least 50% of the glands. In lesions suspected of being adenosis, the absence of basal cell staining in a few glands should not be used as evidence of cancer, as long as these glands resemble their neighbors with patchy basal cell staining.

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