Atypical Lipomatous Tumor/Well-Diff. Liposarcoma : Clinical Features

Comments:
Clinical Features: Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) is a tumor of adults with a peak incidence in 6th and 7th decades of life and shows male predilection. The most common sites of involvement are deep soft tissues of proximal upper and lower extremities (75%) and retroperitoneum (20%). The remainder 5% of cases involve groin, spermatic cord, mediastinum and other rare sites.

In the extremities, they present as painless, slow-growing masses measuring several centimeters. The retroperitoneal tumors produce symptoms associated with an intraabdominal mass. They can reach massive proportions by the time they are discovered.

This intraoperative photograph shows massive enlargement of the entire length of the thigh caused by an ALT/WDL. The resected tumor measured > 40 cm. The diagnosis was confirmed on histologic examination.