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DLBCL : Anaplastic Cells

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HemePath_DLBCL_LN27_Anaplastic.jpg

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The anaplastic variant of diffuse large B-cell lymphoma (DLBCL) has bizarre, highly pleomorphic nuclei as shown here. Multinucleated cells are frequently present. The clinical behavior is the same as conventional DLBCL. It should not be confused with anaplastic large cell lymphoma which is ALK positive and composed of T/null cells.

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