Mantle Cell Lymphoma

Comments:
Nodal involvement by mantle cell lymphoma can show three possible architectural patterns - mantle zone, nodular, or diffuse. This case had a predominant nodular pattern. Transitional areas between different patterns may be seen. When nodularity is prominent, it may be confused with follicular lymphoma at low magnification.

Image courtesy of: Genevieve Crane, MD, PhD; used with permission.