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Mantle Cell Lymphoma : Spleen

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A classic case of mantle cell lymphoma consists of a uniform population of small to medium sized lymphoid cells resembling centrocytes with irregular, indented or clefted nuclear contours. The cells have condensed nuclear chromatin, inconspicuous nucleoli, and a thin rim of cytoplasm. Larger cells such as centroblasts and immunoblasts are absent. Histiocytes with pink cytoplasm are scattered in the background.

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