Follicular Lymphoma : Grade 2
Grade 2 Follicular lymphomas (FLs) have between 6 and 15 centroblasts/hpf. Several centroblasts (with larger round vesicular nuclei and prominent nucleoli) can be clearly recognized in this image. The prognosis of Grade 2 FL is between grades 1 and 3 but closer to grade 1 (i.e. good). Because of the lack of appreciable differences in the clinical behavior between grades 1 and 2, they are now grouped together as low-grade follicular lymphomas.