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Clear Cell Sarcoma-like Tumor of GI Tract

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Clear cell sarcoma-like tumor of gastrointestinal tract is composed of uniform polygonal or rounded cells arranged in sheets with focal pseudopapillary or pseudoalveolar architecture. The well-defined nests of the clear cell sarcoma of soft tissue are not seen.

The cells have moderate amount of clear or lightly eosinophilic cytoplasm, centrally located round nuclei, and punctate or inconspicuous nucleoli. Basophilic macronucleoli of clear cell sarcoma of soft tissue are not seen. Mitotic activity is increased and necrosis is often present.

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