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Adenoma malignum (Minimal Deviation Adenocarcinoma)

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Cervix_MinimalDeviationAdenoCA5.jpg

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Some of the gland are lined by obviously dysplastic cells in this image. Some cases may be associated with Peutz-Jeghers syndrome. More than half of the cases have been found to contain mutations in STK11 a tumor suppressor gene responsible for Peutz-Jeghers syndrome.

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