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Aggressive Angiomyxoma (Deep Angiomyxoma)

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The tumor is composed of bland spindle cells with round or oval nuclei and scant or moderate eosinophilic cytoplasm distributed in a myxoid matrix. Translocations involving chromosome 12 have been documented in a few cases. Aggressive angiomyxoma is usually treated by wide local excision with 1 cm margin.

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