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Luteinized Thecoma : Differential & Treatment

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Ovary_LuteinizedThecoma5_Inhibin.png

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Differential Diagnosis of Luteinized Thecomas: Thecomas with extensive luteinization can resemble steroid cell tumor, stromal hyperthecosis and pregnancy luteoma. Luteinized thecomas with sclerosing peritonitis should be differentiated from stromal hyperthecosis, massive ovarian edema and fibromatosis.

Treatment of Luteinized Thecomas: The treatment is similar to that for typical thecomas and consists of unilateral salpingo-oophorectomy. Endometrial sampling is done to rule out proliferative lesions. Luteinized thecomas with sclerosing peritonitis are treated by excising ovarian tumor along with resection of any affected segments of the bowel, omentectomy and lysis of fibrous adhesions.

The image shows strong inhibin immunoreactivity in clusters of lutein cells and weak positivity in the background thecomatous component in a case of luteinized thecoma.

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