Thecoma : Introduction & Clinical

Comments:
Introduction: Thecoma is an uncommon sex cord-stromal tumor that makes up <1% of all ovarian tumors. It is composed of lipid-containing cells resembling those found in theca interna of a developing follicle.

Clinical Features:Thecoma can occur at any age but usually presents in post-menopausal women (mean age at presentation 59 years). It is rare before puberty. Luteinized thecomas often occur in women under 30 years of age. Thecomas commonly produce estrogen which may cause endometrial proliferative lesions and abnormal uterine bleeding (60% of cases). About 20% of patients develop endometrial carcinoma. Luteinized thecomas produce androgenic manifestations (virilization) in about 10% of cases. Patients may also develop symptoms related to an adnexal mass.