Somatic Neoplasms in Teratoma

Comments:
Somatic Neoplasms in Mature Cystic Teratoma of the Ovary: Somatic-type benign or malignant neoplasms develop in about 2% of mature cystic teratomas of the ovary. The patients are usually in their 5th or 6th decade of life.

Malignant Neoplasms: The most common types are squamous cell carcinoma, carcinoid tumor, and adenocarcinomas. Less common malignant tumors include malignant melanoma, Paget disease, various sarcomas, carcinosarcoma, glioblastoma, central neurocytoma, neuroblastoma, PNET, and mucinous borderline tumor/mucinous adenocarcinoma causing pseudomyxoma peritonei. Mucinous tumors arising in a mature cystic teratoma can mimic primary mucinous ovarian tumor or a metastatic mucinous neoplasm from the appendix.

Benign tumors include blue nevus, sebaceous adenoma, sweat gland tumors, glomus tumor, adrenal adenoma, epithelioid hemangioma, and pituitary adenomas.

About this image: This image shows cyst wall of a mature cystic teratoma of the ovary. The yellowish area was a focus of well-differentiated, keratinizing invasive squamous cell carcinoma.