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Serous Borderline Tumor : Immunohistochemistry

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Ovary_PapillarySerousTumorLMP14.jpg

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Serous borderline tumors express CAM5.2, AE1/AE3, EMA, Ber-EP4, WT1, and PAX8. Estrogen and progesterone receptors are strongly expressed. p53 is wild type.

The image shows irregularly-shaped papillary structures lined by pseudostratified columnar epithelium. The stroma shows spindled as well as sclerotic areas.

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