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Xanthogranulomatous Oophoritis

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Ovary_XanthogranulomatousOophoritis1.jpg

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This is a variant of chronic oophoritis seen in young women with history of pelvic inflammatory disease. It may be the end result of excessive necrosis in a case of oophoritis resulting in abundant lipid breakdown products which are phagocytized by histiocytes. The image shows numerous lipid-laden foamy histiocytes, plasma cells, and lymphocytes. Grossly, it may form solid, yellowish, well-circumscribed multinodular masses.

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