Follow us:        
11,308 Images : Last Website Update : Oct 17, 2021

Large Cell NE Carcinoma

prev
slide 39 of 92
next
No Image
Lungs_Neoplastic_LargeNECarcinoma16.jpg

Close

Comments:
Large cell neuroendocrine carcinomas (LCNEC) have large cells with moderate to abundant quantity of pink cytoplasm. The nuclei have vesicular chromatin and prominent nucleoli an important point of distinction from small cell carcinoma. Mitotic activity is increased (usually > 30 mitoses/2 sq.mm).

Some cases of LCNEC show well-defined areas of squamous cell carcinoma, adenocarcinoma, spindle cell carcinoma, or giant cell carcinoma. Such cases are classified as combined LCNEC and the components clearly identified in the pathology report.

prev
slide 39 of 92
next